Rapid interrogation of the physical and chemical characteristics of salbutamol sulphate aerosol from a pressurised metered-dose inhaler (pMDI)
نویسندگان
چکیده
منابع مشابه
Aerosol deposition in the human lung following administration from a microprocessor controlled pressurised metered dose inhaler.
BACKGROUND Gamma scintigraphy was employed to assess the deposition of aerosols emitted from a pressurised metered dose inhaler (MDI) contained in a microprocessor controlled device (SmartMist), a system which analyses an inspiratory flow profile and automatically actuates the MDI when predefined conditions of flow rate and cumulative inspired volume coincide. METHODS Micronised salbutamol pa...
متن کاملIncorrect use of pressurised metered dose inhaler by asthmatic patients.
The use of pressurised metered dose inhalers was assessed among 93 asthmatic patients attending the respiratory out patient clinic between January to October 1989. They were regular users of the inhalers prior to the assessment. 62.4% of the patients were found to use the inhalers incorrectly. Forty three percent made more than one error. The commonest error observed was the failure to actuate ...
متن کاملEfficacy and safety of ipratropium bromide/salbutamol sulphate administered in a hydrofluoroalkane metered-dose inhaler for the treatment of COPD
BACKGROUND The use of chlorofluorocarbons (CFCs) has contributed to the depletion of the stratospheric ozone layer resulting in serious health concerns. Ipratropium bromide/salbutamol sulphate CFC-pressurized metered-dose inhalers (IB/SAL-CFC pMDI) have been in widespread use for many years without any apparent ill consequences. This combination has now been reformulated using the hydrofluoroal...
متن کاملAccidental Cutaneous Burns Secondary to Salbutamol Metered Dose Inhaler
We report a case of accidental cutaneous burns caused by salbutamol metered dose inhaler. A 9-year-old boy underwent dental extraction at a children's hospital and was incidentally noted to have burn injuries on dorsum of both hands. On questioning, the boy revealed that a few days ago his 14-year-old brother, who is an asthmatic, playfully sprayed his salbutamol metered dose inhaler on the bac...
متن کاملInternal Flow and Near-Orifice Spray Visualisations of a Model Pharmaceutical Pressurised Metered Dose Inhaler
The pressurised Metered Dose Inhaler (pMDI) has become the most prescribed drug delivery system for treating the respiratory diseases. However, the spray generation mechanism of these devices has not been extensively researched and there is very little information regarding the two-phase fluid dynamics associated with pre-atomisation inside the valve stem. The aim of the work presented in this ...
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ژورنال
عنوان ژورنال: Chem. Commun.
سال: 2014
ISSN: 1359-7345,1364-548X
DOI: 10.1039/c4cc05803h